WM-1119

Product Name:	WM-1119
CAT#:	DEHA-2312-LGZ-6
Package:	5mg/10mg/50mg/100mg
Datasheet

Description

WM-1119 is a highly potent and selective inhibitor of lysine acetyltransferase KAT6A with an IC50 of 0.25 μM. It is 1100 times and 250 times more active against KAT6A than against KAT5 or KAT7 respectively.

Basic Information

Synonyms:	WM 1119; WM1119
Application:	Lysine Acetyltransferase KAT6A Inhibitor
CAS Number:	2055397-28-7
Formula:	C18H13F2N3O3S
Molecular Weight:	389.38
SMILES:	O=C(NNS(=O)(C1=CC=CC=C1F)=O)C2=CC(C3=NC=CC=C3)=CC(F)=C2
*Solubility-In vitro:*	DMSO: 69 mg/mL (177.2 mM) Water: Insoluble Ethanol: Insoluble * <1 mg/ml means slightly soluble or insoluble.

Storage

The lyophilized form should be stored at -20°C, in a desiccated environment.
In lyophilized form, the chemical remains stable for 36 months.
In solution, it should be stored at -20°C and used within 3 months to prevent loss of potency. Aliquoting is recommended to avoid multiple freeze/thaw cycles.

Preparing Stock Solutions

0.1 mM_1 mg: 25.68 mL 0.1 mM_5 mg: 128.41 mL 0.1 mM_10 mg: 256.82 mL 0.5 mM_1 mg: 5.14 mL 0.5 mM_5 mg: 25.68 mL 0.5 mM_10 mg: 51.36 mL 1 mM_1 mg: 2.57 mL 1 mM_5 mg: 12.84 mL 1 mM_10 mg: 25.68 mL 5 mM_1 mg: 0.51 mL 5 mM_5 mg: 2.57 mL 5 mM_10 mg: 5.14 mL

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